Contents
Brooks Glycerin 21: Complete Review & Comparison Guide
In-depth review of the Brooks Glycerin 21. See how it compares to similar cushioned trainers, specs, pros, cons, and where to buy.

Brooks Glycerin 21: Complete Review & Comparison Guide
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Overview
The Brooks Glycerin 21 is Brooks' premium cushioned trainer—softer and more luxurious than the Ghost, designed for runners who prioritize comfort on longer runs. With nitrogen-infused DNA LOFT v3 foam, the Glycerin delivers plush cushioning that makes high-mileage training feel easier.
This is the shoe for runners who want to feel pampered on their long runs. The Glycerin doesn't try to be fast or responsive; it focuses entirely on making every step feel soft and comfortable.
Key Specifications
| Spec | Value |
|---|---|
| Category | Daily Trainer, Long Run |
| Cushion Level | High |
| Heel-to-Toe Drop | 10mm |
| Weight (Men's/Women's) | 10.1oz / 9.0oz |
| Stack Height | 38mm heel / 28mm forefoot |
| Pronation Support | Neutral |
| Width Options | Narrow, Standard, Wide |
| MSRP | MSRP: $160 |
| Surface | Road |
What It's Known For
The Glycerin has always been Brooks' soft, plush option, and the 21st version continues that tradition. The nitrogen-infused DNA LOFT v3 foam provides cloud-like cushioning that absorbs impact without feeling dead or unresponsive.
The premium upper complements the soft midsole with comfortable, secure fit. Everything about the Glycerin prioritizes comfort, making it ideal for runners who want to enjoy their miles rather than fight through them.
Why Runners Love It
Pros
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Extremely Soft Cushioning: The DNA LOFT v3 foam delivers plush comfort that makes long runs feel easier.
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Great for Long Runs: The cushioning maintains its character mile after mile, providing consistent comfort.
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Premium Upper: The fit and materials feel luxurious compared to budget options.
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Helpful for Joint Issues: Runners with plantar fasciitis or knee pain often find relief in the Glycerin's soft cushioning.
What Some Runners Don't Like
Cons
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Heavy: At 10.1oz, the Glycerin is heavier than many daily trainers.
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Less Responsive: The soft cushioning prioritizes comfort over energy return.
Who Should Consider This Shoe
The Brooks Glycerin 21 is ideal for:
- High-mileage runners (20-70 miles per week) who need cushioning protection
- Runners who prioritize comfort over speed and responsiveness
- Those with plantar fasciitis or knee pain who benefit from soft cushioning
- Long run specialists who want maximum comfort over distance
How It Compares: Cross-Brand Comparison
| Shoe | Cushion | Drop | Weight (M) | Price | Best For |
|---|---|---|---|---|---|
| Brooks Glycerin 21 | High | 10mm | 10.1oz | MSRP: $160 | Plush daily training |
| Nike Vomero 18 | High | 10mm | 10.6oz | MSRP: $160 | Cushioned long runs |
| ASICS Gel-Nimbus 26 | High | 8mm | 10.4oz | MSRP: $160 | Cushioned neutral |
| Saucony Triumph 22 | High | 10mm | 10.0oz | MSRP: $160 | Cushioned daily training |
| HOKA Clifton 9 | High | 5mm | 9.1oz | MSRP: $145 | Lightweight cushioning |
Brooks Lineup: Same-Brand Comparison
| Shoe | Cushion | Drop | Weight (M) | Price | Best For |
|---|---|---|---|---|---|
| Brooks Glycerin 21 | High | 10mm | 10.1oz | MSRP: $160 | Plush daily training |
| Brooks Ghost 16 | Moderate | 12mm | 9.9oz | MSRP: $140 | Versatile daily training |
| Brooks Glycerin Max 2 | Maximum | 10mm | 11.2oz | MSRP: $180 | Maximum cushion |
| Brooks Glycerin GTS 21 | High | 10mm | 10.4oz | MSRP: $160 | Cushioned stability |
Final Verdict
The Brooks Glycerin 21 delivers premium cushioning for runners who want comfort above all else. The soft DNA LOFT v3 foam makes long runs and easy days feel luxurious.
For runners who prioritize plush cushioning over speed, the Glycerin is one of the best options available. The weight and lack of responsiveness limit versatility, but for its intended purpose, the Glycerin excels.
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Affiliate link - we may earn a commission